Once all of the elements of the PICO format have been identified, you will need to put it together as a "Well-Built" question.
Example:
P: A child under 2 years of age with otitis media.
I: Watchful Waiting
C: Amoxicillin x 10 days
O: Reducing symptoms
Well-Built Question:
In a child under 2 years of age with otitis media, is watchful waiting versus amoxicillin x 10 days as effective in reducing symptoms.
Example:
P: A 45 year old male patient with Bell's Palsy.
I: Valacyclovir
C: Prednisolone
O: Improving facial paralysis
In a patient with Bell's Palsy, is valacyclovir versus prednisolone more effective in improving facial paralysis?
Example:
P: All persons entering the critical care unit
I: Hand rubbing with a waterless, alcohol based solution
C: Hand washing with soap and water
O: Reducing nosocomial infections
For all persons entering the critical care unit, is the addition of hand rubbing with a waterless, alcohol based solution more effective than just hand washing with soap and water in reducing nosocomial infections?